On this page, you can find and book flights from Panama City to Santa Cruz de la Sierra. The distance between the cities is 3,464 km, and service is maintained regularly with 7 flights per week.
The main carrier on this route is CM. Flight prices are constantly changing, so use the price trend chart to find the best deal. We also recommend checking in advance how to get to the airport in Panama City and how to get from the airport in Santa Cruz de la Sierra.
The table shows direct flights Panama City → Santa Cruz de la Sierra on the selected date. The flight takes approximately 5 h. Regular flights are operated by Copa Airlines. Departures from Tocumen International Airport and Marcos A. Gelabert International Airport airports, arrivals at Viru Viru International Airport.
For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.
Below is a calendar of the lowest flight ticket prices for Panama City — Santa Cruz de la Sierra by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from AED 1,342 in y, and the most expensive are around AED 1,755 in r. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.
Panama City → Santa Cruz de la Sierra, average one-way price
| Month | Average price | Level | Month | Average price | Level | Month | Average price | Level |
|---|---|---|---|---|---|---|---|---|
| Jan | AED 2,264 | high | May | AED 1,861 | low | Sep | AED 2,012 | medium |
| Feb | AED 2,012 | medium | Jun | AED 2,214 | high | Oct | AED 1,962 | medium |
| Mar | AED 2,063 | medium | Jul | AED 2,314 | high | Nov | AED 1,912 | low |
| Apr | AED 1,962 | medium | Aug | AED 2,163 | high | Dec | AED 2,365 | high |
Some values are estimated based on seasonality.
The climate in Santa Cruz de la Sierra is characterized by consistently high temperatures in October and November, when the air warms up to 31.5°C. The driest period occurs in July and August, while peak rainfall and high humidity are expected in December and January.
The lowest flight price was recorded for August, starting AED 1,378. The most expensive month for booking is December, when ticket prices start AED 1,755 due to increased holiday demand.
The optimal time to fly is September: during this period, the price starts AED 1,415 with comfortable sunny weather. We recommend avoiding trips in December to save on tickets and avoid the tropical rainy season.
On the route from Panama City to Santa Cruz de la Sierra, the main carrier is Copa Airlines (CM), which provides regular air service between the cities. Direct flights operate daily, making it easy to plan your trip covering a distance of over 3,400 km. The full flight schedule and information on available connections are provided in the list below; click on the airline card for more details.
Flights Panama City — Santa Cruz de la Sierra depart from Tocumen International Airport and Marcos A. Gelabert International Airport and arrive at Viru Viru International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.
The estimated travel time for a direct flight is approximately 4 hours 15 minutes, considering the 3,464 km distance between the cities.
Regular flights from Panama City to Bolivia are operated by Copa Airlines (CM).
Yes, there are direct flights on this route, with an average frequency of about 7 departures per week.
Flight prices are dynamic and depend on the departure date. You can view the current minimum offers for the year ahead in the low-price calendar block on this page.
Flights from Panama City arrive at the international airport of Santa Cruz de la Sierra (SRZ).
Where travelers fly most — pick a route and check prices
